The Authors’ Own Words: We ask authors to describe their impressions regarding the implications of their accepted work, how their findings will change practice, and what is noteworthy about the work.
Raye Z. Litten, PhD; Bonnie B. Wilford, MS; Daniel E. Falk, PhD; Megan L. Ryan, MBA; & Joanne B. Fertig, PhD
Volume 37, 2016 – Issue 2
“Three medications have been approved by the U.S. Food and Drug Administration to treat alcohol dependence (AD): disulfiram, oral and long-acting injectable naltrexone, and acamprosate. Though effective for some, because of the heterogeneity of AD, these medications do not work for all AD patients. A high priority for the National Institute on Alcohol Abuse and Alcoholism (NIAAA) is to develop more efficacious and safe medications, giving clinicians a larger menu of medications from which to choose. With a greater selection of medications, clinicians will be able to better target effective treatment for each individual patient. Over the past decade, several clinical studies have been conducted on a variety of promising medications. This article reviews the efficacy and side-effect profiles of these compounds, offering clinicians a clearer understanding of the current and future medication options available to them.”
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